THE INFLUENCE OF CONTRACEPTIVE TECHNOLOGIES ON THE STATE OF LACTATION AND PROLACTIN LEVELS IN THE BLOOD OF WOMEN AFTER CHILDBIRTH
Abstract
The purpose of this study is to determine the effect of contraceptive technologies on the state of lactation and prolactin levels in the blood of women after childbirth. A certain concern among maternity patients was caused by the possible effect of contraception on lactation. For contraception after childbirth, modern contraceptives were used: intrauterine contraceptives, oral gestagenic drug “Microlut” and injectable gestagenic drug “Depo-provera”. The analysis of the effect of proven contraceptive technologies on the duration of lactation in women using Depo-provera was 26.2±2.3 weeks, microlute-25.7± 1.9 weeks, IUD-21.9± 1.3 weeks. Women who did not use contraception were lactated for 21.5±1.8 weeks. Attention is drawn to longer lactation in women when taking a gestational contraceptive – microlut. Exogenous progestogens injected into the body against the background of postpartum hyperprolactinemia supported it by exerting a direct or indirect effect on the secretion of tyroliberin and dopaminergic substances of opiates of the hypothalamus, prolonging the lactation period. Determining the level of prolactin in the blood of women in the dynamics of contraception confirms this assumption. Prolactin values in lactating women during all the examination periods were higher than in non-lactating women (p < 0.02). The indicator of prolactin level in non-breast-feeding women decreased to normal by 6 months after delivery. In nursing mothers, a decrease to the norm occurred only by the 9th month after childbirth. Clinical indicators of lactation function and the nature of prolactin-synthesizing activity allow us to state that the methods of contraception used do not have an inhibitory effect on lactation, moreover, contraception with gestagenic drugs creates conditions for hyperprolactinemia and prolongation of galactorrhea.
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Bahamondes L., Bahamondes M.V., Modesto W. et al. Effect of hormonal contraceptives during breastfeeding on infant’s milk ingestion and growth. Fertil. Steril. 2013;100:445-450. DOI: 10.1016/j.fertnstert.2013.03.039.
Truitt S.T., Fraser A.B., Grimes D.A. et al. Combined hormonal versus nonhormonal versus progestin-only contraception in lactation. Cochrane Database Syst Rev. 2003;(2):CD003988. DOI: 10.1002/14651858.CD003988.
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Festin M.P.R. Overview of modern contraception. Best Pract Res Clin Obstet Gynaecol 2020; 66: 4–14, https://doi. org/10.1016/j.bpobgyn.2020.03.004.
Bahareva I.V. Kontracepciya posle rodov: optimal’nyj vybor. RMZH. Mat’ i ditya №1 ot 04.03.2020 str. 31-38 DOI: 10.32364/2618-8430-2020-3-1-31-38
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