CYTOKINE REGULATION IN CHRONIC GASTRITIS WITH HELICOBACTER PYLORI-INFECTION

  • Aleksander A. Sinyakov Research Institute of Medical Problems of the North
Keywords: Helicobacter pylori, cytokine regulation, chronic gastritis

Abstract

The aim of our study was to study the content of some cytokines and the features of cytokine regulation in patients with chronic gastritis infected with H. pylori. The study included 3 groups of subjects: the control group, patients with chronic gastritis associated with H. pylori, patients with chronic atrophic gastritis associated with H. pylori. The study measured the levels of IL-2, IL-4, IL-8, TNF-α, interferon-γ in the blood serum of patients and healthy individuals using the enzyme immunoassay method. In patients with HCG and CAH associated with H. pylori, there was an increase in both pro-inflammatory and anti-inflammatory cytokines.

Author Biography

Aleksander A. Sinyakov, Research Institute of Medical Problems of the North

Ph.D., Researcher, Laboratory of Clinical Pathophysiology

References

Список литературы

Na HK, Woo JH. Helicobacter pylori Induces Hypermethylation of CpG Islands Through Upregulation of DNA Methyltransferase: Possible Involvement of Reactive Oxygen/Nitrogen Species. J Cancer Prev. 2014; 19(4):259-264. https://doi.org/10.15430/JCP.2014.19.4.259

Манчук В.Т., Смирнова О.В. Использование методов нейросетевого моделирования и дискриминантного анализа для оценки состояния иммунного статуса у больных острым нелимфобластным лейкозом. Якутский медицинский журнал. 2010; 2 (30) : 77-79

Смирнова О.В., Савченко А.А., Манчук В.Т., И Москов В. Особенности клеточного и гуморального иммунитета у больных острыми нелимфобластным и лимфобластным лейкозами. Сибирский медицинский журнал (Иркутск). 2006; 59 (1): 35-38

Posselt G, Backert S, Wessler S. The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun Signal. 2013;11:77. https://doi.org/10.1186/1478-811X-11-77

Смирнова О.В., Манчук В.Т., Агилова Ю.Н. Роль неспецифического иммунитета при прогрессировании миеломной болезни. Современные проблемы науки и образования. 2014; 2: 515

Смирнова Ольга Валентиновна, Манчук В.Т. Особенности клеток иммунной системы при остром лимфобластном лейкозе. Медицинская иммунология. 2013; 15 (6): 577-584

Смирнова О.В., Титова Н.М., Елманова Н.Г. Роль прооксидантной системы в прогрессировании миеломной болезни. Врач-аспирант. 2013; 60 (5.1): 152-157

References

Na HK, Woo JH. Helicobacter pylori Induces Hypermethylation of CpG Islands Through Upregulation of DNA Methyltransferase: Possible Involvement of Reactive Oxygen/Nitrogen Species. J Cancer Prev. 2014; 19(4):259-264. https://doi.org/10.15430/JCP.2014.19.4.259

Manchuk V.T., Smirnova O.V. Ispol’zovanie metodov nejrosetevogo modelirovaniya i diskriminantnogo analiza dlya ocenki sostoyaniya immunnogo statusa u bol’nyh ostrym nelimfoblastnym lejkozom. YAkutskij medicinskij zhurnal. [Yakut medical journal]. 2010; 2 (30) : 77-79

Smirnova O.V., Savchenko A.A., Manchuk V.T., I Moskov V. Osobennosti kletochnogo i gumoral’nogo immuniteta u bol’nyh ostrymi nelimfoblastnym i limfoblastnym lejkozami. Sibirskij medicinskij zhurnal (Irkutsk). [Siberian Medical Journal (Irkutsk)]. 2006; 59 (1): 35-38

Posselt G, Backert S, Wessler S. The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun Signal. 2013;11:77. https://doi.org/10.1186/1478-811X-11-77

Smirnova O.V., Manchuk V.T., Agilova YU.N. Rol’ nespecificheskogo immuniteta pri progressirovanii mielomnoj bolezni. Sovremennye problemy nauki i obrazovaniya. [Modern problems of science and education]. 2014; 2: 515

Smirnova Ol’ga Valentinovna, Manchuk V.T. Osobennosti kletok immunnoj sistemy pri ostrom limfoblastnom lejkoze. Medicinskaya immunologiya. [Medical immunology]. 2013; 15 (6): 577-584

Smirnova O.V., Titova N.M., Elmanova N.G. Rol’ prooksidantnoj sistemy v progressirovanii mielomnoj bolezni. Vrach-aspirant. [PhD student]. 2013; 60 (5.1): 152-157

Published
2022-12-29
How to Cite
Sinyakov, A. (2022). CYTOKINE REGULATION IN CHRONIC GASTRITIS WITH HELICOBACTER PYLORI-INFECTION. International Journal of Advanced Studies in Medicine and Biomedical Sciences, (2), 54-59. Retrieved from http://sic-publ.press/index.php/mbs/article/view/9
Section
Original Articles